1. Patents
  1. Chemical probes for unfolded, misfolded and intrinsically disordered proteins” PCT/AU2025/050190.
  2. Autophagy sensors” PCT/AU2024/050272.
  3. Compounds with antimicrobial activity” Australian Provisional Patent Application 2022900334.
  4. Tang, B. Z.; Hong, Y.; Leung, W. T. “Specific detection and quantification of cardiolipin and isolated mitochondria by positively charged AIE fluorogens and method of manufacturing thereof” U.S. Patent 10,113,968, 2018.
  5. Tang, B. Z.; Ng, K. M.; Luo, Q.; Yu, Y.; Hong, Y.; Liu, J. Z.; Chen, S. J.; Lam, W. Y. Aggregation induced emission of fluorescent bioprobes and methods of using the same U.S. Patent 9,618,453, 2017.
  6. Tang, B. Z.; Hong, Y.; Chen, S. J.; Leung, W. T.; Zhao, E. G.; Deng, H. Q. Photostable AIE luminogens for specific mitochondrial imaging and its method of manufacturing thereofU.S. Patent US 9,315,465, 2016.
  7. Tang, B. Z.; Hong, Y.; Leung, C. W. T. “AIE luminogens for metal ion detection” U.S. Patent 9,228,949, 2016.
  8. Tang, B. Z.; Hong, Y.; Chen, S. J.; Kwok, R. T. K.; Leung, C. W. T. “Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins” U.S. Patent US 9,279,806, 2016.
  9. Tang, B. Z.; Ng, K. M.; Luo, Q.; Yu, Y.; Hong, Y.; Liu, J. Z.; Chen, S. J.; Lam, W. Y. “Aggregation induced emission active cytophilic fluorescent bioprobes for long-term cell tracking” U.S. Patent 9,409,928, 2016.
  10. Tang, B. Z.; Hong, Y.; Chen, S. J.; Kwok, R. T. K. “Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin” U.S. Patent 8,679,738, 2014; Chinese Patent CN 102706839, 2015; Hong Kong Patent 13101582.7, 2013.
  11. Tang, B. Z.; Hong, Y.; Haussler, M.; Tong, H.; Dong, Y. Q.; Li, Z.; Xing, C. M. “Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same”U.S. Patent  8,129,111, 2012.
  12. Tang, B. Z.; Hong, Y.; Haussler, M.; Tong, H.; Dong, Y. Q.; Li, Z.; Xing, C. M. “Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same” U.S. Patent  7,939,613, 2011.
2. Book Chapters

Zhang, S.; Hong, Y.* Measuring cysteine exposure in unfolded proteins with Tetraphenylethene maleimide” In Torrado, R. P. (ed) The unfolded Protein Response: Methods and Protocols in Methods in Molecular Biology Springer, 2022, vol. 2378, chapter 1, p3-18.

Sabouri, S.; Yao, B.; Hong, Y.* Recent advances in AIE nanoparticles in biomedical applications” In Xu, J., Tang, B. (ed) Aggregation-Induced Emission (AIE) 2022, Elsevier, chapter 15.

Giel, M. C.; Hong, Y.* The application of click chemistry in the design of aggregation-induced emission luminogens for activity-based sensing” In Gu, X., Tang, B. (ed) Aggregation-Induced Emission 2022,De Gruyter, Vol 1, Chapter 4, p53-82.

Luu, T.; Yao, B.; Hong, Y. AIE: New strategies for biosensing and cell imaging” In: Tang Y., Tang B. (eds) Handbook of Aggregation-Induced Emission. Wiley 2021, Chapter 7.

Liu, M.; Hong, Y. Utilisation of tetraphenylethene-derived probes with aggregation-induced emission properties in fluorescence detection of biothiolsIn: Tang Y., Tang B. (eds) Principles and Applications of Aggregation-Induced Emission. Springer, 2019, Chapter 16.

Lim, S.; Tang, B. Z.; Hong, Y. AIE luminogens for visualizing cell structures and functions” In Aggregation-Induced Emission: Materials and Applications Volume 2 ACS Symposium Series, Vol. 1227, 2016, Chapter 8, 199-216.

Leung, C. W. T.; Hong, Y.; Tang, B. Z. “Specific imaging and tracking of mitochondria in live cells by a photostable AIE luminogen” In Advanced Protocols in Oxidative Stress III - Methods in Molecular Biology Humana Press (Clifton, N.J.), 2015, Volume 1208, 21-27.

Hong, Y.; Lam, J. W. Y.; Tang, B. Z. "Applications of aggregation-induced emission materials in biotechnology" In Aggregation-Induced Emission: Applications Wiley: New York, 2013, Chapter 12, 259-274.

3. Selected Publications 2006-2016 (Prior to La Trobe)

# co-first author; *corresponding author

  1. Hong, Y.* Aggregation-Induced Emission-Fluorophores and Applications. Methods and Applications in Fluorescence 2016, 4, 022003. [Invited topical review; Most Read Article]
  2. Chen, S. J.; Hong, Y.;* Zeng, Y.; Sun, Q. Q.; Liu, Y.; Zhao, E. G.; Bai, G. X.; Qu, J. N.; Hao, J. H.; Tang, B. Z., Mapping Live Cell Viscosity by an AIE Fluorogen via Two-photon Fluorescence Lifetime Imaging. Chemistry A European Journal 2015, 21, 4315-4320.
  3. Leung, C. W. T.;# Guo, F.;# Hong, Y.;# Zhao, E. G.; Kwok, R. T. K.; Leung, N. L. C.; Chen, S. J.; Narayanan, N.; El-Agnaf, O.; Tang, Y. H.; Gai, W. P.; Tang, B. Z. Detection of Oligomers and Fibrils of alpha-Synuclein by AIEgen with Strong Fluorescence. Chemical Communications 2015, 51, 1866-1869.
  4. Leung, C. W. T.;# Hong, Y.;# Hanske, J.; Zhao, E. G.; Chen, S. J.; Pletneva, E. V.; Tang, B. Z., Superior Fluorescent Probe for Detection of Cardiolipin. Analytical Chemistry 2014,86,1263-1268.["Researchers report new method to detect key indicator of heart diseases" featured by ScienceDaily, BioSpace, Medindia]
  5. Zhao, E. G.;# Hong, Y.;# Chen, S. J.; Leung, C. W. T.; Chan, C. Y. K.; Kwok, R. T. K.; Lam, J. W. Y.; Tang, B. Z., Highly Fluorescent and Photostable Probe for Long-Term Bacterial Viability Assay Based on Aggregation-Induced Emission. Advanced Healthcare Materials 2014, 3, 88-96. [Higlighted by MaterialsViews]
  6. Mei, J.; Hong, Y.; Lam, J. W. Y.; Qin, A. J.; Tang, Y. H.; Tang, B. Z., Aggregation-Induced Emission: The Whole Is More Brilliant than the Parts. Advanced Materials 2014, 26, 5429-5479. [Highly Cited Paper]
  7. Lou, X. D.;# Hong, Y.;# Chen, S. J.; Leung, C. W. T.; Zhao, N.; Situ, B.; Lam, J. W. Y.; Tang, B. Z., A Selective Glutathione Probe based on AIE Fluorogen and its Application in Enzymatic Activity Assay. Scientific Reports 2014, 4, 4272.
  8. Leung, C. W. T.;# Hong, Y.;# Chen, S. J.; Zhao, E. G.; Lam, J. W. Y.; Tang, B. Z., A Photostable AIE Luminogen for Specific Mitochondrial Imaging and Tracking. Journal of the American Chemical Society 2013,135,62. [Highly Cited Paper]
  9. Chen, S. J.; Hong, Y.; Liu, Y.; Liu, J. Z.; Leung, C. W. T.; Li, M.; Kwok, R. T. K.; Zhao, E. G.; Lam, J. W. Y.; Yu, Y.; Tang, B. Z., Full-Range Intracellular pH Sensing by an Aggregation-Induced Emission Active Two-Channel Ratiometric Fluorogen. Journal of the American Chemical Society 2013,135, 4926. [Highly Cited Paper]
  10. Hong, Y.; Chen, S. J.; Leung, C. W. T.; Lam, J. W. Y.; Tang, B. Z., Water-Soluble Tetraphenylethene Derivatives as Fluorescent “Light-Up” Probes for Nucleic Acid Detection and Their Applications in Cell Imaging. Chemistry An Asian Journal 2013, 8, 1806.
  11. Hong, Y.; Muenzner, J.; Grimm, S. K.; Pletneva, E. V., Origin of Conformational Heterogeneity in the Cardiolipin-bound Cytochrome c. Journal of the American Chemical Society 2012, 134, 18713.
  12. Hong, Y.; Meng, L. M.; Chen, S. J.; Leung, C. W. T.; Da, L. T.; Faisal, M.; Silva, D. A.; Liu, J. Z.; Lam, J. W. Y.; Huang, X. H.; Tang, B. Z., Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics. Journal of the American Chemical Society 2012, 134, 1680. [Highly Cited Paper]
  13. Hong, Y.; Lam, J. W. Y.; Tang, B. Z., Aggregation-Induced Emission. Chemical Society Reviews 2011, 40, 5361. [Highly Cited Paper; Most Accessed Critical Review]
  14. Hong, Y.; Chen, S. J.; Leung, C. W. T.; Lam, J. W. Y.; Liu, J. Z.; Tseng, N. W.; Kwok, R. T. K.; Yu, Y.; Wang, Z. K.; Tang, B. Z., Fluorogenic Zn(II) and Chromogenic Fe(II) Sensors Based on Terpyridine-Substituted Tetraphenylethenes with Aggregation-Induced Emission Characteristics. ACS Applied Materials & Interfaces 2011, 3, 3411.
  15. Hong, Y.; Lam, J. W. Y.; Chen, S. J.; Tang, B. Z., Aggregation-Induced Emission and Biological Application of Tetraphenylethene Luminogens. Australian Journal of Chemistry 2011, 64, 1203.
  16. Hong, Y.; Feng, C.; Yu, Y.; Liu, J. Z.; Lam, J. W. Y.; Luo, K. Q.; Tang, B. Z. Quantitation, Visualization, and Monitoring of Conformational Transitions of Human Serum Albumin by a Tetraphenylethene Derivative with Aggregation-Induced Emission Characteristics. Analytical Chemistry 2010, 82, 7035.
  17. Hong, Y.; Xiong, H.; Lam, J. W. Y.; Haussler, M.; Liu, J. Z.; Yu, Y.; Zhong, Y. C.; Sung, H. H. Y.; Williams, I. D.; Wong, K. S.; Tang, B. Z., Fluorescent Bioprobes: Structural Matching in the Docking Processes of Aggregation-Induced Emission Fluorogens on DNA Surfaces. Chemistry A European Journal 2010, 16, 1232.
  18. Hong, Y.; Haussler, M.; Lam, J. W. Y.; Li, Z.; Sin, K. K.; Dong, Y. Q.; Tong, H.; Liu, J. Z.; Qin, A. J.; Renneberg, R.; Tang, B. Z., Label-Free Fluorescent Probing of G-Quadruplex Formation and Real-Time Monitoring of DNA Folding by a Quaternized Tetraphenylethene Salt with Aggregation-Induced Emission Characteristics. Chemistry A European Journal 2008, 14, 6428.
  19. Tong, H.; Hong, Y.; Dong, Y. Q.; Ren, Y.; Haussler, M.; Lam, J. W. Y.; Wong, K. S.; Tang, B. Z., Color-Tunable, Aggregation-Induced Emission of a Butterfly-Shaped Molecule Comprising a Pyran Skeleton and Two Cholesteryl Wings. Journal of Physical Chemistry B 2007, 111, 2000.
  20. Tong, H.; Hong, Y.; Dong, Y. Q.; Haussler, M.; Lam, J. W. Y.; Li, Z.; Guo, Z. F.; Guo, Z. H.; Tang, B. Z., Fluorescent "Light-up" Bioprobes based on Tetraphenylethylene Derivatives with Aggregation-Induced Emission Characteristics. Chemical Communications 2006, 3705.

4. New AIEgens with delayed fluorescence for fluorescence imaging and fluorescence lifetime imaging of living cells
Gan, S.; Zhou, J.; Smith, T. A.; Su, H.; Luo, W.; Hong, Y.; Zhao, Z.; Tang, B. Z., Materials Chemistry Frontiers 2017, 1, 2554-2558. (2017)
5. AIE conjugated polyelectrolytes based on tetraphenylethene for efficient fluorescence imaging and lifetime imaging of living cells
Gao, M.; Hong, Y.; Chen, B.; Wang, Y.; Zhou, W.; Wong, W.; Zhou, J.; Smith, T.A.; Zhao, Z., Polymer Chemistry 2017, 8, 3862-3866. (2017)
6. 9-Vinylanthracene Based Fluorogens: Synthesis, Structure-Property Relationships and Applications
Liu, M.; Onchaiya, S.; Tan, L.; Haghighatbin, M. A.; Luu, T.; Owyong, T. C.; Hushiarian, R.; Hogan, C. F.; Smith, T. A.; Hong, Y.*, Molecules 2017, 22, 2148. (2017)
7. Measuring macromolecular crowding in cells through fluorescence anisotropy imaging with an AIE fluorogen
Soleimaninejad, H.; Chen, M. Z.; Lou, X. D.; Smith, T. A.*; Hong, Y.*, Chemical Communications 2017, 53, 2874-2877. (2017)
8. Monitoring Early-Stage Protein Aggregation by an Aggregation-Induced Emission Fluorogen
Kumar, M.; Hong, Y.*; Thorn, D. C.; Ecroyd, H.; Carver, J. C.*, Analytical Chemistry 2017, 89, 9322-9329. (2017)

Featured as a Technical Note by BMG Labtech

9. A thiol probe for measuring unfolded protein load and proteostasis in cells
Chen, M. Z.; Moily, N.; Bridgford, J.; Wood, R.; Radwan, M.; Smith, T. A.; Song, Z.; Tang, B. Z.; Tilley, L.; Xu, X.; Reid, G.; Pouladi, M.; Hong, Y.*; Hatters, D. M.*, Nature Communications 2017, 8, 474. (2017)
10. Amyloid aggregation and membrane activity of the antimicrobial peptide uperin 3.5
Martin, L. L.; Kubeil, C.; Piantavigna, S.; Tikkoo, T.; Gray, N. P.; John, T.; Calabrese, A. N.; Liu, Y.; Hong, Y.; Hossai, M. A.; Patil, N.; Abel, B.; Hoffmann, R.; Bowie, J. H.; Carver, J. A., Peptide Science 2018, 110, e24052. (2018)
11. A water-soluble, AIE-active polyelectrolyte for conventional and fluorescence lifetime imaging of mouse neuroblastoma neuro-2A cells
Wang, Y.; Yao, H.; Zhou, J.; Hong, Y.; Chen, B.; Zhang, B.; Smith, T. A.; Wong, W. W. H.; Zhao, Z., Journal of Polymer Science Part A, 2018, 56, 672-680. (2018)
12. Synthesis and X-Ray Crystallographic Characterisation of Frustum-Shaped Ligated [Cu18H16(DPPE)6]2+ and [Cu16H14(DPPA)6]2+ Nanoclusters and Studies on Their H2 Evolution Reactions
Li, J.; Ma, H. Z.; Reid, G.; Alison, J.; Hong, Y.; White, J. M.; Mulder, R. J.; O’Hair, R., Chemistry A European Journal 2018, 24, 2070-2074. (2018)
13. Biochromic silole derivatives: a single dye for differentiation, quantitation and imaging of live/dead cells
Chen, S.; Liu, J.; Zhang, S.; Zhao, E.; Yu, C.; Hushiarian, R.; Hong, Y.*; Tang, B. Z.*, Materials Horizons 2018, 5, 969-978. (2018)
14. Biothiol-specific fluorescent probes with aggregation-induced emission characteristics
Ding, S.; Liu, M.; Hong, Y., Science China Chemistry 2018, 61, 882-891. (2018)
15. Amphiphilic Tetraphenylethene-Based Pyridinium Salt for Selective Cell-Membrane Imaging and Room-Light-Induced Special Reactive Oxygen Species Generation
Zhang, W.; Huang, Y.; Chen, Y.; Zhao, E.; Hong, Y.; Chen, S.; Lam, J.; Chen, Y.; Hou, J.; Tang, B. Z., ACS Applied Materials & Interfaces 2019, 11, 10567-10577. (2019)
16. The Kinetics of Amyloid Fibrillar Aggregation of Uperin 3.5 Is Directed by the Peptide’s Secondary Structure
John, T.; Dealey, T. J. A.; Gray, N. P.; Patil, N. A.; Hossain, M. A.; Abel, B.; Carver, J. A.; Hong, Y.; Martin, L. L., Biochemistry 2019, 58, 3656-3668. (2019)
17. Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production
Hu, M.; Schulze, K. E.; Ghildyal, R.; Henstridge, D. C.; Kolanowski, J. L.; New, E. J.; Hong, Y.; Hsu, A. C.; Hansbro, P. M.; Wark, P. A. B.; Bogoyevitch, M. A.; Jans, D. A., eLife 2019, 8, e42448. (2019)
18. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity
Hu, D.; Sun, X.; Liao, X.; Zhang, X.; Zarabi, S.; Schimmer, A.; Hong, Y.; Ford, C.; Luo, Y.; Qi, X., Acta Neuropathologica 2019, 137, 939-960. (2019)
19. A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K+ solution
Liu, C.; Zhou, B.; Geng, Y.; Tam, D. Y.; Feng, R.; Miao, H.; Xu, N.; Shi, X.; You, Y.; Hong, Y.; Tang, B. Z.; Lo, P. K.; Kuryavyi, V.; Zhu, G., Chemical Science 2019, 10, 218-226. (2018)
20. Copper ions trigger disassembly of neurokinin B functional amyloid and inhibit de novo assembly
Jayawardena, B. M.; Jones, M. R.; Hong, Y.; Jones, C. E., Journal of Structural Biology 2019, 208, 107394. (2019)
21. Aptamer-Based Biosensing with a Cationic AIEgen
Luu, T.; Liu, M.; Chen, Y.; Hushiarian, R.; Cass, A.; Tang, B. Z.; Hong, Y.*, Australian Journal of Chemistry 2019, 72, 620-626. (2019)
22. A Maleimide-functionalized Tetraphenylethene for Measuring and Imaging Unfolded Proteins in Cells
Zhang, S.; Liu, M.; Tan, L. Y. F.; Hong, Q.; Pow, Z. L.; Owyong, T. C.; Ding, S.; Wong, W. W. H.; Hong, Y.*, Chemistry An Asian Journal 2019, 14, 904-909. (2019)
23. Hexaphenyl-1,3-butadiene derivative: a novel “turn-on” rapid fluorescent probe for intraoperative pathological diagnosis of hepatocellular carcinoma
Chen, D.; Mao, H.; Hong, Y.; Tang, Y.; Zhang, Y.; Li, M.; Dong, Y., Materials Chemistry Frontier 2020, 4, 2716-2722. (2020)
24. Detection of biomarkers in body fluids using bioprobes based on aggregation-induced emission fluorogens
Zhang, X.; Yao, B.; Hu, Q.; Hong, Y.; Wallace, A.; Reynolds, K.; Ramsey, C.; Maeder, A.; Reed, R.; Tang, Y., Materials Chemistry Frontier 2020, 4, 2548-2570. (2020)
25. An α-Cyanostilbene Derivative for the Enhanced Detection and Imaging of Amyloid Fibril Aggregates
Marzano, N. R.; Wray, K. M.; Johnston, C. L.; Paudel, B. P.; Hong, Y.; van Oijen, A.; Ecroyd, H., ACS Chemical Neuroscience 2020, 11, 4191-4202. (2020)
26. The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models
Parakh, S.; Shadfar, S.; Perri, E. R.; Ragagnin, A. M. G.; Piattoni, C. V.; Fogolín, M. B.; Yuan, K. C.; Shahhyedari, H.; Don, E. K.; Thomas, C. J.; Hong, Y.; Comini, M. A.; Laird, A. S.; Spencer, D. M.; Atkin, J. D., iScience 2020, 101097. (2020)
27. Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal
Hidalgo San Jose, L.; Sunshine, M. J.; Dillingham, C. H.; Chua, B. A.; Kruta, M.; Hong, Y.; Hatters, D. M.; Signer, R. A. J., Cell Reports 2020, 30, 69-80. (2019)
28. A Spectroscopic Marker for Structural Transitions Associated with Amyloid-β Aggregation
Das A.; Gupta, A.; Hong, Y.; Carver, J.; Maiti, S., Biochemistry, 2020, 59, 1813-1822. (2020)
29. Tumor-Triggered Disassembly of a Multiple-Agent-Therapy Probe for Efficient Cellular Internalization
Yang, J.; Dai, J.; Wang, Q.; Cheng, Y.; Guo, J.; Zhao, Z.; Hong, Y.; Lou, X.; Xia, F., Angewandte Chemie International Edition 2020, 132, 20405-20410. (2020)
30. Barbituric acid based fluorogens: synthesis, aggregation-induced emission, and protein fibril detection
Ding, S.; Yao, B.; Schobben, L.; Hong, Y.*, Molecules 2020, 25, 32. (2019)
31. Diaminomaleonitrile-functionalised schiff bases: synthesis, solvatochromism, and lysosome-specific imaging
Ding, S.; Yao, B.; Chen, M.; Liu, C.; Owyong, T. C.; Johnston, A.; Hong, Y.*, Journal of Chemistry 2020, 73, 942-947. (2019)
32. Aggregation-Induced Emission Photosensitizers: From Molecular Design to Photodynamic Therapy
Dai, J.; Wu, X.; Lou, X.*; Xia, F.; Wang, S.; Hong, Y.*, Journal Of Medicinal Chemistry 2020, 63, 1996-2012. (2020)
33. Optimising molecular rotors to AIE fluorophores for mitochondria uptake and retention
Owyong, T. C.; Ding, S.; Wu, N.; Fellowes, T.; Chen, S.; White, J. M.; Wong, W. W. H.*; Hong, Y.*, Chemical Communications 2020, 56, 14853-14856. (2020)
34. The fluorescence toolbox for visualizing autophagy
Ding, S.; Hong, Y.*, Chemical Society Reviews 2020, 49, 8354-8389. (2020)
35. A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment
Owyong, T. C.; Subedi, P.; Deng, J.; Hinde, E.; Paxman, J. J.; White, J. M.; Chen, W.; Heras, B.; Wong, W. W. H.*; Hong, Y.*, Angewandte Chemie International Edition 2020, 132, 10215-10221. (2019)

"Molecular probe maps misfolded proteome state in live cells" featured by ScienceDaily & Phys.org

"Sensing protein wellbeing" featured by EurekAlert! AAAS, ChemistryViews, Bionity, & PressReleasePoint,

"New molecular probe senses the state of proteome in live cells" featured by The Medical News

36. In Situ Monitored Vortex Fluidic-Mediated Protein Refolding/Unfolding Using an Aggregation-Induced Emission Bioprobe
Hu, Q.; Hu, H.; Zhang, X.; Fan, K.; Hong, Y.; Raston, C. L.; Tang, Y., Molecules, 2021, 26, 4273. (2021)
37. Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
Liu, X.; Yu, J.; Xu, L.; Umphred-Wilson, K.; Peng, F.; Ding, Y.; Barton, B. M.; Lv, X.; Zhao, M. Y.; Sun, S.; Hong, Y.; Qi, L.; Adoro, S.; Chen, X., eLife, 2021, 10, e69975. (2021)
38. Fluorescence Imaging and Photodynamic Inactivation of Bacteria Based on Cationic Cyclometalated Iridium(III) Complexes with Aggregation-Induced Emission Properties
Ho, P. Y.; Lee, S. Y.; Kam, C.; Zhu, J.; Shan, G. G.; Hong, Y.; Wong, W. Y.; Chen, S., Advanced Healthcare Materials 2021, 10, 2100706. (2021)
39. Recent Applications of Aggregation Induced Emission Probes for Antimicrobial Peptide Studies
Luu, T.; Li, W.;* O’Brien-Simpson, N. M; Hong, Y.*, Chemistry An Asian Journal 2021, 16, 1027-2040. (2021)
40. Detection of urinary albumin using a “turn-on” fluorescent probe with aggregation-induced emission characteristics.
Hu, Q.; Yao, B.; Owyong, T. C.; Prashanth, S.; Wang, C.; Zhang, X.; Wong, W. W. H.; Tang, Y.;* Hong, Y.*, Chemistry An Asian Journal 2021, 16, 1245-1252. (2021)
41. Red blood cell membrane-camouflaged nanoparticles loaded with AIEgen and Poly(I : C) for enhanced tumoral photodynamic-immunotherapy
Dai, J.; Wu, M.; Wang, Q.; Ding, S.; Dong, X.; Xue, L.; Zhu, Q.; Zhou, J.; Xia, F.;* Wang, S.;* Hong, Y.*, National Science Review 2021, 8, nwab039. (2021)
42. Detection of kidney disease biomarkers based on fluorescence technology
Yao, B.; Giel, M.-C.; Hong, Y.*, Materials Chemistry Frontier 2021, 5, 2124-2142. (2021)
43. Recent advances in bioanalytical methods to measure proteome stability in cells
Zhang, S.; Greening, D. W.*; Hong, Y.*, Analyst 2021, 146, 2097-2109. (2021)
44. Construction of a Highly Sensitive Thiol-Reactive AIEgen-Peptide Conjugate for Monitoring Protein Unfolding and Aggregation in Cells
Sabouri, S.; Liu, M.; Zhang, S.; Yao, B.; Soleimaninejad, H.; Baxter, A. A.; Armendariz-Vidales, G.; Subedi, P.; Duan, C.; Lou, X.; Hogan, C. F.; Heras, B.; Poon, I. K. H.; Hong, Y.*, Advanced Healthcare Materials 2021, 10, 2101300. (2021)
45. Synthesis and evaluation of benzochalcogenazole-benzimidazole derivatives as potential DNA-binding radioprotectors
Fellowes, T.; Skene, C. E.; Martin, R. F.; Lobacheysky, P.; Owyong, T. C.; Hong, Y. N.; White, J. M., ARKIVOC 2022, 80-98. (2022)

46. Polymerization-amplified photoacoustic signal by enhancing near-infrared light-harvesting capacity and thermal-to-acoustic conversion
Gao, H.-Q.; Zhang, J.-T.; Qi, X.-W.; Jiao, D.; Hong, Y.; Shan, K.; Kong, X.-L.; Ding, D., Chinese Journal of Polymer Science 2022, 40, 1090-1100. (2022)
47. Brush-like Polymer Prodrug with Aggregation-Induced Emission Features for Precise Intracellular Drug Tracking
Naghibi, S.; Sabouri, S.; Hong, Y.; Jia, Z.; Tang, Y., Biosensors 2022, 12, 373. (2022)
48. Novel Formulation of Undecylenic Acid induces Tumor Cell Apoptosis
Day, Z. I.; Mayfosh, A. J.; Giel, M. C.; Hong, Y.; Williams, S. A.; Santavanond, J. P.; Rau, T. F.; Poon, I. K.; Hulett, M. D., International Journal Of Molecular Sciences 2022, 23, 14170. (2022)
49. A supramolecular self-assembled nanomaterial for synergistic therapy of immunosuppressive tumor
Wang, T. J.; Gao, Z. Y.; Zhang, Y. F.; Hong, Y.; Tang, Y. H.; Shan, K.; Kong, X. L.; Wang, Z. M.; Shi, Y.; Ding, D., Journal Of Controlled Release 2022, 351, 272-283. (2022)
50. Semiconducting Polymer Nanoparticles with Surface-Mimicking Protein Secondary Structure as Lysosome-Targeting Chimaeras for Self-Synergistic Cancer Immunotherapy
Qi, J.; Jia, S. R.; Kang, X. Y.; Wu, X. Y.; Hong, Y.; Shan, K.; Kong, X. L.; Wang, Z. M.; Ding, D., Advanced Materials 2022, 34, 202203309. (2022)
51. An Activatable Near-Infrared Afterglow Theranostic Prodrug with Self-Sustainable Magnification Effect of Immunogenic Cell Death
Gao, Z. Jia, S.; Ou, H.; Hong, Y.; Shan, K.; Kong, X.; Wang, Z.; Feng, G.; Ding, D., Angewandte Chemie International Edition 2022, 61, e202209793. (2022)
52. Fluorescent Reporters for Antimicrobial Peptides
Hong, Y.*; Li, W.*, Australian Journal of Chemistry 2022, 75, 2-8. (2021)
53. The synthesis and application of a colour-switch β-arylethenesulfonyl fluoride fluorescent probe in the detection of serum albumin
Giel, M. C.; Owyong, T. C.; Hong, Y.* , Australian Journal of Chemistry 2022, 75, 877-883. (2022)
54. Synthesis of a β-Arylethenesulfonyl Fluoride-Functionalized AIEgen for Activity-Based Urinary Trypsin Detection
Giel, M.-C.; Zhang, S.; Hu, Q.; Ding, D.; Tang, Y.; Hong, Y.*, ACS Applided Bio Materials 2022, 5, 4321-4326 (2022)
55. Emerging fluorescence tools for the study of proteostasis in cells.
Owyong, T. C.; Hong, Y.*, Current Opinion In Chemical Biology 2022, 67, 102116. (2022)
56. Development and application of Diels-Alder adducts displaying AIE properties
Gialelis, T. L.; Owyong, T. C.; Ding, S.; Li, W.; Yu, M.; O’Brien-Simpson, N. M; Zhao, Z.; White, J. M.; B. Yao; Hong, Y.*, Cell Reports Physical Science 2022, 3, 100766. (2022)
57. RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells
Chavez, F. H.; Luo, H.; Cifani, P.; Pine, A.; Chu, K.; Joshi, S. Barin, E.; Schurer, A.; Chan, M.; Chang, K.; Han, G.; Pierson, A.; Xiao, M.; Yang, X.; Kuehm, L.; Hong, Y.; Nguyen, D.; Chiosis, G.; Kentsis, A.; Leslie, C.; Vu, L. Kharas, M. , Nature Communications volume 14, Article number: 2290 (2023) (2023)
58. Platelet membrane camouflaged AIEgen-mediated photodynamic therapy improves the effectiveness of anti-PD-L1 immunotherapy in large-burden tumors
Dai, J.; Wu, M.; Xu, Y.; Yao, H.; Lou, X.; Hong, Y.; Zhou, J.; Xia, F.; Wang, S., Bioengineering & Translational Medicine 2023, 8 (2), e10417. (2022)
59. CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response
Jutzi, J. S.; Marneth, A. E.; Jiménez-Santos, M. J.; Hem, J.; Guerra-Moreno, A.; Rolles, B.; Bhatt, S.; Myers, S. A.; Carr, S. A.; Hong, Y.; Pozdnyakova, O.; van Galen, P.; Al-Shahrour, F.; Nam. A. S.; Mullally, A., Leukemia 2023, 37 (2), 359-369. (2023)
60. Detection of Unfolded Cellular Proteins Using Nanochannel Array with Probe-functionalized Outer-surfaces
Qiao, Y.; Hu, J.-J.; Hu, Y.; Duan, C.; Jiang, W.; Ma, Q.; Hong, Y.; Huang, W.-H.; Xia, F.; Lou, X. , Angewandte Chemie International Edition 2023, 62, e202309671. (2023)
61. The effect of tailing lipidation on the bioactivity of antimicrobial peptides and their aggregation tendency
Lin, B.; Hung, A.; Singleton, W.; Darmawan, K. K.; Moses, R.; Yao, B.; Wu, H.; Barlow, A.; Sani, M. A.; Sloan, A. J.; Hossain, M. A.; Wade, J. D.; Hong, Y.; O’Brien-Simpson, N. M; Li, W., Aggregate 2023, e329. (2023)
62. Aggregation-Induced Emission (AIE), Life and Health
Wang, H.; …Ding, S.;...Hong, Y.*; …Owyong, T.C.;...Tang, B. Z.* , ACS Nano 2023, 17(15), 14347–14405 (2023)
63. A General Fluorescence-Based Method for Quantifying and Mapping Biomolecular Polarity In Vitro and In Cells
Owyong, T. C.; O'Shea, R.; Lee, M.; White, J. M.; Donnelly, P. S.; Hinde, E.; Wong, W. W.; Hong, Y.*, bioRxiv 2023, 2023.2002. 2007.526546. (2023)
64. Click chemistry in the design of AIEgens for biosensing and bioimaging
Giel, M. C.; Hong, Y.*, Aggregate 2023, e336. (2023)
65. Small molecule fluorescent probes for the study of protein phase separation
Owyong, T. C.; Zhao, J.; Hong, Y.*, Current Opinion In Chemical Biology 2023 (2023)
66. A novel red-emitting aggregation-induced emission probe for determination of β-glucosidase activity
Yao, B.; Zhao, J.; Ding, S.; Giel, M.-C.; Zhang, G.; Ding, D.; Tang, Y.; Weng, Z. H.*; Hong, Y.*, Biomaterials 295, 122046 (2023)
67. Protein disulfide isomerase endoplasmic reticulum protein 57 (ERp57) is protective against ALS-associated mutant TDP-43 in neuronal cells
Parakh, S.; Perri, E. R.; Vidal, M.; Takalloo, Z.; Jagaraj, C. J.; Mehta, P.; Yang, S.; Thomas, C. J.; Blair, I. P.; Hong, Y.; Atkin, J. D., NeuroMolecular Medicine 2024, 26, 23. (2024)
68. Aggregation-prone antimicrobial peptides target gram-negative bacterial nucleic acids and protein synthesis
Chen, P.; Zhang, T.; Li, C.; Praveen, P.; Parisi, K.; Beh, C.; Ding, S.; Wade, J. D.; Hong, Y.; Li, S.; Nkoh, J. N.; Hung, A.; Li, W.;* Shang, C.*, Acta Biomaterialia 2024, DOI: 10.1016/j.actbio.2024.12.002. (2024)


69. Spatiotemporally controllable covalent bonding of RNA for multi-protein interference
Fang, H.; Wang, T.; Dai, J.; Hu, J.; Chen, Z.; Yuan, L.; Hong, Y.; Xia, F.; Lou, X., Advanced Healthcare Materials 2024, 2304108. (2024)
70. Deregulated protein homeostasis constrains fetal hematopoietic stem cell pool expansion in Fanconi anemia
Kovuru, N.; Mochizuki-Kashio, M.; Menna, T.; Jeffrey, G.; Hong, Y.; Yoon, Y. M.; Zhang, Z.; Kurre, P. , Nature Communications 2024, 15, 1852. (2024)
71. Development of NIAD-4 derivatives for fluorescence-based detection of protein aggregates
Owyong, T. C.; Shippey, L. E.; Ding, S.; Owen, D. S.; Zhang, S.; White, J. M.; Wong, W. W. H.; Smith, D. P.; Hong, Y.*, Sensors & Diagnostics 2024, DOI: 10.1039/D4SD00182F. (2024)
72. Functionalized α-cyanostilbene derivatives for detection of hypoxia or proteostasis imbalance in live cells
Zhao, J.;# Zaheer, M.;# You, J.; Owyong, T. C.; Giel, M.-C.; Praveen, P.; Li, W.; Hou, J.; Hogan, C. F.; Zhao, E.; Ding, S.;* Hong, Y.*, Chemistry A European Journal 2024, 30, e202402630. (2024)
73. A novel fluorogenic probe reveals lipid droplet dynamics in ME/CFS fibroblasts
Ding, S.; Sanislav, O.; Missailidis, D.; Allan, C. Y.; Owyong, T. C.; Wu, M. Y.; Chen, S. J.; Fisher, P. R.; Annesley, S. J.; Hong, Y.*, Advanced Sensor Research 2024, 3, 2300178 (2024)
74. Global analysis of endogenous proteindisorder in cells
Zhang, S.;# Owyong, T. C.;# Sanislav, O.; Englmaier, L.; Sui, X.; Wang, G.; Greening, D. W.; Williamson, N. A.; Villunger, A.; White, J. M.; Heras, B.; Wong, W. W. H.; Fisher, P. R.; Hong, Y.* , Nature Methods 2025, 22, 124–134. (2024)
75. IRE1α–XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs
Barton, B. M.; Son, F.; Verma, A.; Bal, S. K.; Tang, Q.; Wang, R.; Umphred-Wilson, K.; Khan, R.; Trichka, J.; Dong, H.; Lentucci, C.; Chen, X.; Chen, Y.; Hong, Y.; Duy, C.; Elemento, O.; Melnick, A. M.; Cao, J.; Chen, X.; Glimcher, L. H.; Adoro, S., Nature Immunology 2025, 26, 200–214 (2025)
76. Profiling the disordered proteome in cells using a chemical tag
Owyong, T. C.; Zhang, S.*, Nature Reviews Molecular Cell Biology (2025)
77. Publications (2017-)

*Corresponding; #co-first